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Treatment with corticosteroids (especially prednisolone ≥20 mg/day or equivalent) is associated with an increased risk of infection. However, it is unclear whether corticosteroid therapy is associated with an increased risk of developing COVID-19 or its complications. Data on budesonide, a topical corticosteroid with low systemic bioavailability, show that these drugs are associated with significantly fewer side effects compared to systemic corticosteroids and their side effects are close to placebo. If possible, corticosteroids should be avoided and a rapid dose reduction considered, and a switch to budesonide is recommended. This must be taken into account, taking into account the risk of exacerbation of CKD. If a patient with COPD is in contact with a person with COVID-19 or develops COVID-19, it is recommended to gradually reduce the dose of corticosteroids, the use of budesonide is preferred, but taking into account the severity of COPD and the risk of exacerbation.
Реагирование на такие эпидемические вызовы очень сложны как организационно, так и финансово. Результат оценивается с течением времени при хорошо организованном эпидемиологическом надзоре. Согласно утвержденному плану реагирования на вспышку полиомиелита, возникшему в начале октября 2021 г., удалось только 1 февраля 2022 г. начать 1-й тур кампании. Он должен был длиться 3 недели и имел целью вакцинировать ИПВ 140 тыс. детей в возрасте от 6 мес. до 6 лет, пропустивших вакцинацию согласно Календарю. Практически к концу 3-й недели 1-го тура по состоянию на 18.02.2022 г. было провакцинировано лишь 28% детей от запланированного количества. Поэтому решили продлить 1-й тур еще дополнительно на 2 недели, что снова не было исполнено в связи с началом войны. Таким образом, фактически реагирования на вспышки полиомиелита не произошло.
Experts refer to the third category of skin manifestations as pink lichen and papulosquamous rashes, which are infectious-allergic skin lesions associated with COVID-19 infection. The clinical feature of pink lichen in this case is the absence of maternal plaque. The fourth category includes a measles rash. To the fifth - toxicodermia. This rash is associated with individual intolerance of patients of certain groups of drugs. The sixth category of skin manifestations of coronavirus infection, scientists include urticaria, which in some cases may be a harbinger of the onset of COVID-19.
Mikhail Yurchuk is from the Khmelnytsky region. After school, the man worked at a glass factory and a furniture factory. However, at the age of 26, he decided to become a professional military man. “Since childhood, I have dreamed of becoming a military man. For me, this is about honor, duty. First, I served in a missile brigade, I was a rocket scientist, then I went to a military college for non-commissioned officers and finally went to the airborne brigade,” says Mikhail Yurchuk. When a full-scale war began, the military served in the Donbass. Then the brigade was moved to the Kharkov region. Michael was wounded there.
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