Пульс - медицинский центр 
Пульс - медицинский центр
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бесплатно по России
Back in 2002, according to the justification of the Institute, inactivated polio vaccine (IPV) was introduced into the Immunization Calendar of Ukraine for the 1st vaccination against poliomyelitis (children continued to receive OPV for the remaining 5 doses by age). In 2006, this vaccine was also used for the second vaccination. This made it possible to first reduce and then practically stop the cases of vaccine-associated paralytic poliomyelitis in Ukraine. Since then, the issue of switching to a full IPV vaccination scheme in Ukraine has been repeatedly raised, as has been practiced for many years in all European countries, the USA, Canada, and Australia. Currently, this problem is becoming even more urgent, given both the epidemic situation and the prospects for Ukraine's accession to the EU.
In 2021, in Ukraine, vaccination coverage rates for children under 1 year of age against such infections as tuberculosis, measles, whooping cough, diphtheria, poliomyelitis, hepatitis B, etc. ranged from 78% to 80.1% (with the required level >90 %), which is undoubtedly not enough to recognize the epidemic situation under control. In particular, this figure for 3 vaccinations against polio at the age of up to 1 year was 80.1%, 5 vaccinations at the age of 6 years received only 78.4% of children. At the same time, vaccination coverage rates varied widely across regions. In 12 regions, among children under 1 year old, they were <80% and ranged from 68.5% to 73.9%, and among children under 18 months. (4 vaccinations) - 66% to 73%. That is, almost 20-30% of children did not receive routine vaccination against poliomyelitis due to age in the above target groups, subject to vaccination according to the Immunization Schedule.
If a patient tests positive for SARS-CoV-2 and/or develops COVID-19, discontinuation of biologics should be considered until the patient clears the infection. JAK inhibitors (tofacitinib and others) selectively affect the intracellular JAK/STAT signaling system, which mediates the action of many cytokines involved in the pathogenesis of ulcerative colitis. Unlike genetically engineered biological drugs, inhibition
At present, the risk of increased circulation of vaccine-related polioviruses and associated outbreaks with a low level of vaccination coverage against the background of the use of an oral vaccine is also complicated by military operations in the country, leading to the destruction of the infrastructure of cities and towns, intensive migration and evacuation of the population. Ukraine, and to regions where there are no active hostilities (Chernivtsi, Transcarpathian, Lvov, Volyn regions). These areas were the ones with the lowest polio vaccination rates in 2021.
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