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Moreover, low vitamin D levels common in patients with CVD may increase the risk and severity of COVID-19. This is because vitamin D increases levels of anti-inflammatory cytokines and reduces viral replication, which in turn can reduce pro-inflammatory cytokines that contribute to lung damage. Despite the lack of evidence demonstrating increased susceptibility to COVID-19, drugs used in the treatment of COPD increase the risk of respiratory tract infections to varying degrees. However, theoretically, some immunosuppressive drugs may have beneficial effects, given that the cause of death in COVID-19 is a cytokine storm leading to acute respiratory failure.
If a patient tests positive for SARS-CoV-2 and/or develops COVID-19, discontinuation of biologics should be considered until the patient clears the infection. JAK inhibitors (tofacitinib and others) selectively affect the intracellular JAK/STAT signaling system, which mediates the action of many cytokines involved in the pathogenesis of ulcerative colitis. Unlike genetically engineered biological drugs, inhibition
Михаил Юрчук родом из Хмельницкой области. После школы мужчина работал на стеклозаводе и мебельной фабрике. Однако в 26 лет решил стать профессиональным военным. "Я с детства мечтал стать военным. Для меня это о чести, долге. Сначала я служил в ракетной бригаде, был ракетчиком, потом — военный колледж сержантского состава и наконец пошел в десантную бригаду", — говорит Михаил Юрчук. Когда началась полномасштабная война, военный служил в Донбассе. Затем бригаду переместили в Харьковскую область. Там Михаил получил ранение.
“For the second month, we see an increase in the number of coronavirus diseases. Over the past week, 24,000 new cases were recorded, the week before that there were 16,000, that is, there is a gradual increase. Our experts, together with WHO experts, predict that this year the peak incidence will be at the beginning October... In previous years, it was the end of October - the beginning of November. We are preparing for this in order to provide proper medical care," the minister said.
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