When transitioning to biological therapy, subcutaneous administration should be considered to limit patient contact with the healthcare facility. Selective switching from intravenous infliximab to subcutaneous anti-TNF is not recommended as it may increase the risk of relapse. If the patient is in contact with a COVID-19 person, withdrawal of anti-TNF therapy for 2 weeks should be considered.
В настоящее время риск усиления циркуляции вакцинородственных полиовирусов и связанных с ними вспышек при низком уровне охвата прививками на фоне применения оральной вакцины осложняется еще и военными действиями в стране, приводящими к разрушению инфраструктур городов и населенных пунктов, интенсивной миграции и эвакуации населения. Украины, так и в регионы, где отсутствуют активные боевые действия (Черновицкая, Закарпатская, Львовская, Волынская обл.). Именно в этих областях отмечались самые низкие уровни вакцинации против полиомиелита в 2021 году.
The current COVID-19 pandemic caused by SARS-CoV-2 has become a global health emergency. Treatment of chronic inflammatory bowel disease (CIBD) according to the standards includes the use of 5-aminosalicylic acid (5-ASA), corticosteroids, cytostatics, and biological therapy. However, these treatments can weaken the immune system, which potentially puts COPD patients at increased risk of infections and infectious diseases, including COVID-19. Therefore, patients with CVD have a greater risk of developing COVID-19 and more severe clinical course, or even death, compared to the general population.
Regardless of the period of the life cycle, it is necessary to increase self-esteem of health by optimizing the social environment, introducing the basics of a healthy lifestyle (in particular, various forms of self-realization, regular physical education and sports of optimal intensity, fitness, yoga, etc.). After all, inadequate self-assessment of one's own health can change a person's behavior in a negative direction, lead to the health of destructive or deviant forms of behavior.