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The use of thiopurine (azathioprine and mercaptopurine) reduces the immune response to viruses, which is associated with an increased risk of opportunistic infections. There is limited evidence that they increase the risk of respiratory infections. The risks and benefits should be considered, but most patients can continue on a stable dose. In patients in stable remission, elderly patients and in the presence of concomitant pathology, it is recommended to stop taking thiopurine. During a pandemic, it is recommended to avoid starting thiopurine or increasing the dose, which will allow patients to avoid potential side effects. If the patient is in contact with a COVID-19 person, temporary withdrawal of thiopurine for 2 weeks should be considered. If a patient tests positive for SARS-CoV-2 and/or develops COVID-19, temporary discontinuation of thiopurine may be recommended until the patient clears the infection.

In the age group of 44-60 years, 47% of men and 66% of women rated their own health as "good" (p<0.05). A feature of the self-assessment of health of the respondents of this age group was higher levels of subjective assessment of health in women compared to men: about 2% of women subjectively assessed their own health as "excellent"; the proportion of women who rated their health as "mediocre" was two times less compared to men (32% versus 17%; p<0.05). In the group of older people (over 61 years of age), gender characteristics of the distribution of self-assessment of health by respondents were also established. Thus, half of the men surveyed rated their own health as “good”, which was three times more than women (53% versus 18%, p<0.01). In women, on the contrary, the share of those who rated their own health as “mediocre” was 17% higher. Almost every fifth woman of this age considers her own health to be “bad”, while not a single man gave such an assessment. High health scores (“excellent” and “very good”) were absent for both men and women.

Thus, hypertension has been and remains a very important medical and social problem that requires appropriate attention not only from healthcare institutions and medical workers, but also from the leadership of the Ministry of Health and the state. Only through the joint efforts of representatives of medical science, health care and the entire public society can it be possible to achieve an increase in the effectiveness of the fight against this disease

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Первичная артериальная гипертензия (АГ) или гипертоническая болезнь (ГБ) остается одним из наиболее распространенных сердечно-сосудистых заболеваний. Длительное и стойкое повышение артериального давления (АД) приводит к поражению органов-мишеней, способствуя развитию тяжелых сердечно-сосудистых осложнений (мозгового инсульта, инфаркта миокарда, жизненно опасных нарушений ритма и сердечной недостаточности), поражений почек (почечной недостаточности) и зрения и обуславливает высокую смертность и инвалидизацию населения трудоспособного возраста. Ежегодно в мире гипертензия является причиной смерти более 10 млн. человек. В Украине зарегистрировано более 12,6 млн. человек с этой болезнью, или более 35% населения. Но, сСреди лиц с повышенным артериальным давлением (АД) знают о наличии болезни только 52% больных, из них лечатся менее трети, причем эффективно лечится не более 15% больных.


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