Thus, hypertension has been and remains a very important medical and social problem that requires appropriate attention not only from healthcare institutions and medical workers, but also from the leadership of the Ministry of Health and the state. Only through the joint efforts of representatives of medical science, health care and the entire public society can it be possible to achieve an increase in the effectiveness of the fight against this disease
В Україні кожен 3-й дорослий має підвищений артеріальний тиск. Така сама тенденція спостерігається і у світі. Через високий тиск зростає ризик розвитку мозкового інсульту, інфаркту міокарда, серцевої чи ниркової недостатності. У світі підвищений артеріальний тиск спричиняє близько 7,5 мільйонів смертей щороку. Це понад 12% від загальної кількості.
The use of thiopurine (azathioprine and mercaptopurine) reduces the immune response to viruses, which is associated with an increased risk of opportunistic infections. There is limited evidence that they increase the risk of respiratory infections.
The risks and benefits should be considered, but most patients can continue on a stable dose. In patients in stable remission, elderly patients and in the presence of concomitant pathology, it is recommended to stop taking thiopurine.
During a pandemic, it is recommended to avoid starting thiopurine or increasing the dose, which will allow patients to avoid potential side effects.
If the patient is in contact with a COVID-19 person, temporary withdrawal of thiopurine for 2 weeks should be considered.
If a patient tests positive for SARS-CoV-2 and/or develops COVID-19, temporary discontinuation of thiopurine may be recommended until the patient clears the infection.
If a patient tests positive for SARS-CoV-2 and/or develops COVID-19, discontinuation of biologics should be considered until the patient clears the infection.
JAK inhibitors (tofacitinib and others) selectively affect the intracellular JAK/STAT signaling system, which mediates the action of many cytokines involved in the pathogenesis of ulcerative colitis. Unlike genetically engineered biological drugs, inhibition
Пульс - медицинский центр 
Пульс - медицинский центр
