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Пульс - медицинский центр
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“For the second month, we see an increase in the number of coronavirus diseases. Over the past week, 24,000 new cases were recorded, the week before that there were 16,000, that is, there is a gradual increase. Our experts, together with WHO experts, predict that this year the peak incidence will be at the beginning October... In previous years, it was the end of October - the beginning of November. We are preparing for this in order to provide proper medical care," the minister said.
Применение тиопурина ( азатиоприн и меркаптопурин ) снижает иммунный ответ на вирусы, что связано с повышенным риском оппортунистических инфекций. Существует ограниченное количество доказательств, что они повышают риск инфекций респираторной системы. Следует учесть риски и преимущества, но большинство пациентов могут продолжать прием стабильной дозы. У пациентов в стадии устойчивой ремиссии, пожилых пациентов и при наличии сопутствующей патологии рекомендуется прекратить прием тиопурина.
Treatment with corticosteroids (especially prednisolone ≥20 mg/day or equivalent) is associated with an increased risk of infection. However, it is unclear whether corticosteroid therapy is associated with an increased risk of developing COVID-19 or its complications. Data on budesonide, a topical corticosteroid with low systemic bioavailability, show that these drugs are associated with significantly fewer side effects compared to systemic corticosteroids and their side effects are close to placebo. If possible, corticosteroids should be avoided and a rapid dose reduction considered, and a switch to budesonide is recommended. This must be taken into account, taking into account the risk of exacerbation of CKD. If a patient with COPD is in contact with a person with COVID-19 or develops COVID-19, it is recommended to gradually reduce the dose of corticosteroids, the use of budesonide is preferred, but taking into account the severity of COPD and the risk of exacerbation.
On March 11, 2020, the World Health Organization declared the novel severe respiratory syndrome coronavirus (SARS-CoV-2) a pandemic. The number of cases worldwide is constantly growing, the infection is a serious threat to health, especially in the case of old age, immunodeficiency and the presence of concomitant diseases. There are now a growing number of reports and preliminary observations indicating that the COVID-19 virus can also infect the skin. Skin lesions ranging from "covid fingers" to hives can be potential signs of coronavirus. The flow of information about the skin manifestations of coronavirus infection prompts the development of a classification of these lesions.
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