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Более того, низкие уровни витамина D, характерные для пациентов с ХОККом, могут повышать риск и тяжесть течения COVID-19. Это объясняется тем, что витамин D способствует увеличению уровня противовоспалительных цитокинов и снижает репликацию вирусов, что, в свою очередь, может снизить провоспалительные цитокины, способствующие повреждению легких. Несмотря на отсутствие доказательств, демонстрирующих повышенную восприимчивость к COVID-19, лекарства, используемые в терапии ХОЗК, увеличивают риск инфекций дыхательных путей в разной степени. Однако теоретически некоторые иммуносупрессивные препараты могут иметь положительные эффекты, учитывая, что причиной смерти при COVID-19 является цитокиновый шторм, приводящий к острой дыхательной недостаточности.
Skin lesions in coronavirus infection caused by the SARS-CoV-2 virus are divided into seven categories. The first category includes skin angiitis caused directly by COVID-19 infection, against which the walls of small vessels of the dermis are damaged by immune complexes circulating in the blood. Angiitis is localized on the skin of the upper and lower extremities. They look like frostbite, painful, itchy. Such manifestations usually occur in young patients with a mild course of the disease, appear in the late stages and last about 12 days. The second category includes papular-vesicular rashes, which are characterized by acute clinical manifestations in the form of chickenpox, more similar to prickly heat, occurring against a background of high fever and increased sweating.
Primary arterial hypertension (AH) or essential hypertension (AH) remains one of the most common cardiovascular diseases. A prolonged and persistent increase in blood pressure (BP) leads to damage to target organs, contributing to the development of severe cardiovascular complications (cerebral stroke, myocardial infarction, life-threatening arrhythmias and heart failure), kidney damage (renal failure) and vision and causes high mortality and disability of the working-age population. Annually in the world hypertension is the cause of death of more than 10 million people. In Ukraine, more than 12.6 million people are registered with this disease, or more than 35% of the population. But, among people with high blood pressure (BP), only 52% of patients know about the presence of the disease, less than a third of them are treated, and no more than 15% of patients are effectively treated.
Analyzing the subjective assessment of health by student youth (under the age of 25), we found the following: the vast majority of respondents, regardless of gender, rated their own health as "good" and "very good". Almost half of the guys and every fifth girl noted the criterion for assessing "excellent" health. About 2% of boys and 3% of girls noted that they have “excellent” health. The criteria for assessing the health of "mediocre" and "poor" for the children practically did not differ. Thus, “mediocre” health was observed in 15% of boys and 14% of girls; "bad" - 2% of boys and 2% of girls.
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