Пульс - медицинский центр 
Пульс - медицинский центр
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The use of thiopurine (azathioprine and mercaptopurine) reduces the immune response to viruses, which is associated with an increased risk of opportunistic infections. There is limited evidence that they increase the risk of respiratory infections. The risks and benefits should be considered, but most patients can continue on a stable dose. In patients in stable remission, elderly patients and in the presence of concomitant pathology, it is recommended to stop taking thiopurine. During a pandemic, it is recommended to avoid starting thiopurine or increasing the dose, which will allow patients to avoid potential side effects. If the patient is in contact with a COVID-19 person, temporary withdrawal of thiopurine for 2 weeks should be considered. If a patient tests positive for SARS-CoV-2 and/or develops COVID-19, temporary discontinuation of thiopurine may be recommended until the patient clears the infection.
В возрастной группе 44-60 лет 47% мужчин и 66% женщин оценили собственное здоровье как «хорошее» (р<0,05). Особенностью самооценки здоровья респондентов данной возрастной группы были более высокие уровни субъективной оценки здоровья у женщин, по сравнению с мужчинами: около 2% женщин субъективно оценили собственное здоровье как «отличное»; доля женщин, оценивших здоровье как «посредственное» была в два раза меньше по сравнению с мужчинами (32% против 17%; р<0,05).
In regions where there are no active hostilities, it is necessary to intensify the process of polio vaccination of both local and displaced children under 6 years of age with an additional dose of inactivated vaccine and continue vaccination by age in accordance with the Immunization Schedule against all infectious diseases controlled by specific means. For the prevention of poliomyelitis, preference should be given to an inactivated vaccine for all
Back in 2002, according to the justification of the Institute, inactivated polio vaccine (IPV) was introduced into the Immunization Calendar of Ukraine for the 1st vaccination against poliomyelitis (children continued to receive OPV for the remaining 5 doses by age). In 2006, this vaccine was also used for the second vaccination. This made it possible to first reduce and then practically stop the cases of vaccine-associated paralytic poliomyelitis in Ukraine. Since then, the issue of switching to a full IPV vaccination scheme in Ukraine has been repeatedly raised, as has been practiced for many years in all European countries, the USA, Canada, and Australia. Currently, this problem is becoming even more urgent, given both the epidemic situation and the prospects for Ukraine's accession to the EU.
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