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Имеющаяся пандемия COVID-19, вызванная SARS-CoV-2, приобрела масштабы чрезвычайного положения в области мирового здравоохранения. Лечение хронических воспалительных заболеваний кишечника (ХЗОК) согласно стандартам включает применение препаратов 5-аминосалициловой кислоты (5-АСК), кортикостероидов, цитостатиков, а также биологическую терапию. Однако эти методы лечения могут ослабить иммунную систему, которая потенциально подвергает пациентов с ХОЗК повышенному риску инфекций и инфекционных заболеваний, включая COVID-19. Следовательно, пациенты с ХОККом имеют больший риск развития COVID-19 и более тяжелого клинического течения, или даже смерти, по сравнению с населением в целом.
The use of thiopurine (azathioprine and mercaptopurine) reduces the immune response to viruses, which is associated with an increased risk of opportunistic infections. There is limited evidence that they increase the risk of respiratory infections. The risks and benefits should be considered, but most patients can continue on a stable dose. In patients in stable remission, elderly patients and in the presence of concomitant pathology, it is recommended to stop taking thiopurine. During a pandemic, it is recommended to avoid starting thiopurine or increasing the dose, which will allow patients to avoid potential side effects. If the patient is in contact with a COVID-19 person, temporary withdrawal of thiopurine for 2 weeks should be considered. If a patient tests positive for SARS-CoV-2 and/or develops COVID-19, temporary discontinuation of thiopurine may be recommended until the patient clears the infection.
The use of thiopurine (azathioprine and mercaptopurine) reduces the immune response to viruses, which is associated with an increased risk of opportunistic infections. There is limited evidence that they increase the risk of respiratory infections. The risks and benefits should be considered, but most patients can continue on a stable dose. In patients in stable remission, elderly patients and in the presence of concomitant pathology, it is recommended to stop taking thiopurine. During a pandemic, it is recommended to avoid starting thiopurine or increasing the dose, which will allow patients to avoid potential side effects. If the patient is in contact with a COVID-19 person, temporary withdrawal of thiopurine for 2 weeks should be considered. If a patient tests positive for SARS-CoV-2 and/or develops COVID-19, temporary discontinuation of thiopurine may be recommended until the patient clears the infection.
During the fighting near Izyum in the spring of 2022, military Mikhail Yurchuk received a complex wound. As a result, the man lost an arm and a leg. First, he was fitted with a prosthetic leg, and recently at the Lviv National Rehabilitation Center "Indestructible" - a modern bionic prosthetic arm. Thanks to special sensors, it can reproduce familiar movements. Now the warrior is undergoing rehabilitation. This was reported in the First TMO Lviv.
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