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Пульс - медицинский центр
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The use of thiopurine (azathioprine and mercaptopurine) reduces the immune response to viruses, which is associated with an increased risk of opportunistic infections. There is limited evidence that they increase the risk of respiratory infections. The risks and benefits should be considered, but most patients can continue on a stable dose. In patients in stable remission, elderly patients and in the presence of concomitant pathology, it is recommended to stop taking thiopurine. During a pandemic, it is recommended to avoid starting thiopurine or increasing the dose, which will allow patients to avoid potential side effects. If the patient is in contact with a COVID-19 person, temporary withdrawal of thiopurine for 2 weeks should be considered. If a patient tests positive for SARS-CoV-2 and/or develops COVID-19, temporary discontinuation of thiopurine may be recommended until the patient clears the infection.
According to him, now there are 5.5 thousand patients in hospitals who have been diagnosed with coronavirus disease. Of these, 2,300 are on beds with oxygen therapy, and most of them receive it. To prevent logistical problems, at the end of last year, state funding was allocated through several mechanisms: one in the form of centralized purchases, one in the form of subventions provided to the regions in order to purchase autonomous sources of oxygen supply. On September 15, the Ministry of Health sent 124,608 packages of the Paxclovid drug for coronavirus disease to the regions. The medicine is prescribed primarily to patients at risk to prevent the complex course of coronavirus disease.
Thus, hypertension has been and remains a very important medical and social problem that requires appropriate attention not only from healthcare institutions and medical workers, but also from the leadership of the Ministry of Health and the state. Only through the joint efforts of representatives of medical science, health care and the entire public society can it be possible to achieve an increase in the effectiveness of the fight against this disease
В период пандемии рекомендуется избежать начала приема тиопурина или увеличения дозы, что позволит пациентам избежать потенциальных побочных эффектов. Если пациент находится в контакте с человеком COVID-19, необходимо рассмотреть возможность временного отказа от приема тиопурина на 2 недели. Если у пациента положительный результат теста на SARS-CoV-2 и/или у него развивается COVID-19, возможно рекомендовать временное прекращение приема тиопурина до тех пор, пока пациент не избавится от инфекции.
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