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Если пациент находится в контакте с человеком COVID-19, необходимо рассмотреть возможность временного отказа от приема тофацитиниба в течение 2 недель. Если у пациента положительный результат теста на SARS-CoV-2 и/или у него развивается COVID-19, необходимо рассмотреть возможность отказа от приема тофацитиниба до тех пор, пока пациент не избавится от инфекции.
The criteria for assessing their own health by young people (25-44 years old - according to the WHO classification) were distributed as follows: almost half of the respondents, regardless of gender, rated their own health as "good"; every 4th of those surveyed - as "very good"; “Mediocre” health was noted by every fifth woman and every tenth person; almost the same was the proportion of respondents who rated their own health as “bad”; the level of subjective assessment of "excellent health" was observed in every tenth man, while in women it was absent.
On March 11, 2020, the World Health Organization declared the novel severe respiratory syndrome coronavirus (SARS-CoV-2) a pandemic. The number of cases worldwide is constantly growing, the infection is a serious threat to health, especially in the case of old age, immunodeficiency and the presence of concomitant diseases. There are now a growing number of reports and preliminary observations indicating that the COVID-19 virus can also infect the skin. Skin lesions ranging from "covid fingers" to hives can be potential signs of coronavirus. The flow of information about the skin manifestations of coronavirus infection prompts the development of a classification of these lesions.
Considering that a similar picture took place in previous years, in Ukraine there was an accumulation of a layer susceptible to poliomyelitis among the child population. In addition, since April 2016, the oral (live) polio vaccine (OPV), which is used in Ukraine, since the 3rd vaccination, does not contain type 2 poliovirus (two-component OPV, which is now used worldwide, contains only polioviruses). ). type ov1 and 3). This also contributes to a decrease in both individual and population immunity to type 2 poliovirus. The result was an outbreak of poliomyelitis caused by vaccine-derived type 2 poliovirus (a vaccine-derived virus that acquired neurovirulent properties during circulation in a low immune population.). There was no adequate response to this outbreak, namely additional vaccination rounds for children under 6 years of age to stop the circulation of the vaccine-related virus. In January 2022, a new outbreak emerged.
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