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Thus, hypertension has been and remains a very important medical and social problem that requires appropriate attention not only from healthcare institutions and medical workers, but also from the leadership of the Ministry of Health and the state. Only through the joint efforts of representatives of medical science, health care and the entire public society can it be possible to achieve an increase in the effectiveness of the fight against this disease

In 2021, in Ukraine, vaccination coverage rates for children under 1 year of age against such infections as tuberculosis, measles, whooping cough, diphtheria, poliomyelitis, hepatitis B, etc. ranged from 78% to 80.1% (with the required level >90 %), which is undoubtedly not enough to recognize the epidemic situation under control. In particular, this figure for 3 vaccinations against polio at the age of up to 1 year was 80.1%, 5 vaccinations at the age of 6 years received only 78.4% of children. At the same time, vaccination coverage rates varied widely across regions. In 12 regions, among children under 1 year old, they were <80% and ranged from 68.5% to 73.9%, and among children under 18 months. (4 vaccinations) - 66% to 73%. That is, almost 20-30% of children did not receive routine vaccination against poliomyelitis due to age in the above target groups, subject to vaccination according to the Immunization Schedule.

Более того, низкие уровни витамина D, характерные для пациентов с ХОККом, могут повышать риск и тяжесть течения COVID-19. Это объясняется тем, что витамин D способствует увеличению уровня противовоспалительных цитокинов и снижает репликацию вирусов, что, в свою очередь, может снизить провоспалительные цитокины, способствующие повреждению легких. Несмотря на отсутствие доказательств, демонстрирующих повышенную восприимчивость к COVID-19, лекарства, используемые в терапии ХОЗК, увеличивают риск инфекций дыхательных путей в разной степени. Однако теоретически некоторые иммуносупрессивные препараты могут иметь положительные эффекты, учитывая, что причиной смерти при COVID-19 является цитокиновый шторм, приводящий к острой дыхательной недостаточности.

The first and mandatory step in the treatment of hypertension is lifestyle modification (LS), which is aimed at correcting the above risk factors, primarily modifiable ones. A big problem is the choice of the most optimal treatment for hypertension, which can slow down the progression of lesions of the heart, blood vessels, kidneys, brain and eyes. The vast majority of hypertensive patients who seek medical help require combination antihypertensive therapy. At the same time, the most appropriate at the present level is the use of fixed combinations of such drugs.

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