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If a patient tests positive for SARS-CoV-2 and/or develops COVID-19, discontinuation of biologics should be considered until the patient clears the infection. JAK inhibitors (tofacitinib and others) selectively affect the intracellular JAK/STAT signaling system, which mediates the action of many cytokines involved in the pathogenesis of ulcerative colitis. Unlike genetically engineered biological drugs, inhibition

К наиболее частым заболеваниям, которые ассоциируются с АГ относятся: ожирение, прежде всего абдоминальное ожирение (АО), сахарный диабет (СД) 2 типа, ишемическая болезнь сердца (ИБС), нарушение ритма и проводимости, хроническая болезнь почек (ХХН), цереброваскулярные заболевания, заболевания суставов, хроническая обструктивная болезнь легких, синдром сонного апноэ, заболевания щитовидной железы и другие эндокринные заболевания.

Analyzing the subjective assessment of health by student youth (under the age of 25), we found the following: the vast majority of respondents, regardless of gender, rated their own health as "good" and "very good". Almost half of the guys and every fifth girl noted the criterion for assessing "excellent" health. About 2% of boys and 3% of girls noted that they have “excellent” health. The criteria for assessing the health of "mediocre" and "poor" for the children practically did not differ. Thus, “mediocre” health was observed in 15% of boys and 14% of girls; "bad" - 2% of boys and 2% of girls.

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The most common diseases associated with hypertension include: obesity, primarily abdominal obesity (AO), type 2 diabetes mellitus (DM), coronary heart disease (CHD), arrhythmias and conduction disorders, chronic kidney disease (CKD), cerebrovascular diseases , joint diseases, chronic obstructive pulmonary disease, sleep apnea syndrome, thyroid disease and other endocrine diseases. In this regard, the 2018 European Society of Hypertension and European Society of Cardiology guidelines emphasized the need for careful stratification of cardiovascular and overall risk of complications in order to select the most optimal antihypertensive therapy.


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