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In 2021, in Ukraine, vaccination coverage rates for children under 1 year of age against such infections as tuberculosis, measles, whooping cough, diphtheria, poliomyelitis, hepatitis B, etc. ranged from 78% to 80.1% (with the required level >90 %), which is undoubtedly not enough to recognize the epidemic situation under control. In particular, this figure for 3 vaccinations against polio at the age of up to 1 year was 80.1%, 5 vaccinations at the age of 6 years received only 78.4% of children. At the same time, vaccination coverage rates varied widely across regions. In 12 regions, among children under 1 year old, they were <80% and ranged from 68.5% to 73.9%, and among children under 18 months. (4 vaccinations) - 66% to 73%. That is, almost 20-30% of children did not receive routine vaccination against poliomyelitis due to age in the above target groups, subject to vaccination according to the Immunization Schedule.

Experts refer to the third category of skin manifestations as pink lichen and papulosquamous rashes, which are infectious-allergic skin lesions associated with COVID-19 infection. The clinical feature of pink lichen in this case is the absence of maternal plaque. The fourth category includes a measles rash. To the fifth - toxicodermia. This rash is associated with individual intolerance of patients of certain groups of drugs. The sixth category of skin manifestations of coronavirus infection, scientists include urticaria, which in some cases may be a harbinger of the onset of COVID-19.

Skin lesions in coronavirus infection caused by the SARS-CoV-2 virus are divided into seven categories. The first category includes skin angiitis caused directly by COVID-19 infection, against which the walls of small vessels of the dermis are damaged by immune complexes circulating in the blood. Angiitis is localized on the skin of the upper and lower extremities. They look like frostbite, painful, itchy. Such manifestations usually occur in young patients with a mild course of the disease, appear in the late stages and last about 12 days. The second category includes papular-vesicular rashes, which are characterized by acute clinical manifestations in the form of chickenpox, more similar to prickly heat, occurring against a background of high fever and increased sweating.

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Лечение кортикостероидами (особенно преднизолоном в дозе ≥20 мг/сут или его эквивалент) связано с повышенным риском инфицирования. Однако неясно, связана ли терапия кортикостероидами с повышенным риском развития COVID-19 или ее осложнений. Данные о будесониде , кортикостероидах местного действия с низкой системной биодоступностью показывают, что эти препараты связаны со значительно меньшим количеством побочных эффектов по сравнению с системными кортикостероидами и их побочные эффекты приближены к плацебо.


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