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В период пандемии рекомендуется избежать начала приема тиопурина или увеличения дозы, что позволит пациентам избежать потенциальных побочных эффектов. Если пациент находится в контакте с человеком COVID-19, необходимо рассмотреть возможность временного отказа от приема тиопурина на 2 недели. Если у пациента положительный результат теста на SARS-CoV-2 и/или у него развивается COVID-19, возможно рекомендовать временное прекращение приема тиопурина до тех пор, пока пациент не избавится от инфекции.

Considering that a similar picture took place in previous years, in Ukraine there was an accumulation of a layer susceptible to poliomyelitis among the child population. In addition, since April 2016, the oral (live) polio vaccine (OPV), which is used in Ukraine, since the 3rd vaccination, does not contain type 2 poliovirus (two-component OPV, which is now used worldwide, contains only polioviruses). ). type ov1 and 3). This also contributes to a decrease in both individual and population immunity to type 2 poliovirus. The result was an outbreak of poliomyelitis caused by vaccine-derived type 2 poliovirus (a vaccine-derived virus that acquired neurovirulent properties during circulation in a low immune population.). There was no adequate response to this outbreak, namely additional vaccination rounds for children under 6 years of age to stop the circulation of the vaccine-related virus. In January 2022, a new outbreak emerged.

Specialists of the Laboratory of Epidemiological Research and Medical Informatics of the State Institution “Institute of Public Health named after A.I. O.M. Marzeeva NAMNU” researched the issues of health status, its subjective feeling, as well as behavior that contributes to health or is risky among people of all ages. Assessment by adolescents and young people of their own health, life satisfaction is important for the development of both preventive programs and directions for promoting health. At the same time, it is also important for the elderly and elderly to maintain an active lifestyle, maintain health, work (self-realization), and overcome the so-called biological determinism. It is reasonable to consider the social environment as an important determinant of health. In this regard, the question of optimizing the social environment arises, since in the absence of a comfortable social environment focused on human development, there are actually no constructive conditions for the formation of good health.

In the age group of 44-60 years, 47% of men and 66% of women rated their own health as "good" (p<0.05). A feature of the self-assessment of health of the respondents of this age group was higher levels of subjective assessment of health in women compared to men: about 2% of women subjectively assessed their own health as "excellent"; the proportion of women who rated their health as "mediocre" was two times less compared to men (32% versus 17%; p<0.05). In the group of older people (over 61 years of age), gender characteristics of the distribution of self-assessment of health by respondents were also established. Thus, half of the men surveyed rated their own health as “good”, which was three times more than women (53% versus 18%, p<0.01). In women, on the contrary, the share of those who rated their own health as “mediocre” was 17% higher. Almost every fifth woman of this age considers her own health to be “bad”, while not a single man gave such an assessment. High health scores (“excellent” and “very good”) were absent for both men and women.

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