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Treatment with corticosteroids (especially prednisolone ≥20 mg/day or equivalent) is associated with an increased risk of infection. However, it is unclear whether corticosteroid therapy is associated with an increased risk of developing COVID-19 or its complications. Data on budesonide, a topical corticosteroid with low systemic bioavailability, show that these drugs are associated with significantly fewer side effects compared to systemic corticosteroids and their side effects are close to placebo. If possible, corticosteroids should be avoided and a rapid dose reduction considered, and a switch to budesonide is recommended. This must be taken into account, taking into account the risk of exacerbation of CKD. If a patient with COPD is in contact with a person with COVID-19 or develops COVID-19, it is recommended to gradually reduce the dose of corticosteroids, the use of budesonide is preferred, but taking into account the severity of COPD and the risk of exacerbation.

К шестой категории кожных проявлений коронавирусной инфекции ученые относят крапивницу, которая в некоторых случаях может быть предвестником начала COVID-19 . К последней (седьмой) категории можно отнести артифициальные (трофические) изменения тканей лица, возникшие у пациентов с искусственной вентиляцией легких и из-за длительного лежания на животе. Приведенные классификации были первыми описаниями поражений кожи при COVID-19 и поэтому приводились разные признаки: те, что были вызваны именно COVID-19 , и те, которые возникали вследствие различных причин, в частности, связанных с лечением заболевания. В связи с тем, что эти поражения нуждались в различных подходах как в лечении, так и в проведении противоэпидемических или мер предосторожности, мы, исходя из опыта всех этих месяцев наблюдения за больными, предлагаем классификацию поражений кожи, ассоциированные с COVID-19 . выложить следующим образом

A separate problem is the treatment of hypertension in patients with COVID-19. The presence of a history of hypertension in patients with COVID-19 was associated with a more severe course of infection, in contrast to patients who did not have hypertension. According to modern concepts, during the COVID-19 pandemic, patients with hypertension should carefully monitor their blood pressure levels and take constantly prescribed medications. This also applies to the use of so-called blockers of the renin-angiotensin system for the treatment of patients with hypertension: angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers. A number of recent studies show that these groups of drugs not only do not increase the risk of infection with the virus, but also significantly improve the course of coronavirus disease.

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At present, the risk of increased circulation of vaccine-related polioviruses and associated outbreaks with a low level of vaccination coverage against the background of the use of an oral vaccine is also complicated by military operations in the country, leading to the destruction of the infrastructure of cities and towns, intensive migration and evacuation of the population. Ukraine, and to regions where there are no active hostilities (Chernivtsi, Transcarpathian, Lvov, Volyn regions). These areas were the ones with the lowest polio vaccination rates in 2021.


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