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Specialists of the Laboratory of Epidemiological Research and Medical Informatics of the State Institution “Institute of Public Health named after A.I. O.M. Marzeeva NAMNU” researched the issues of health status, its subjective feeling, as well as behavior that contributes to health or is risky among people of all ages. Assessment by adolescents and young people of their own health, life satisfaction is important for the development of both preventive programs and directions for promoting health. At the same time, it is also important for the elderly and elderly to maintain an active lifestyle, maintain health, work (self-realization), and overcome the so-called biological determinism. It is reasonable to consider the social environment as an important determinant of health. In this regard, the question of optimizing the social environment arises, since in the absence of a comfortable social environment focused on human development, there are actually no constructive conditions for the formation of good health.

Большой проблемой является выбор наиболее оптимального лечения АГ, способного затормозить прогрессирование поражений сердца, сосудов, почек, головного мозга и глаз. Подавляющему большинству больных АГ, которые обращаются за медицинской помощью, требуется назначение комбинированной антигипертензивной терапии. При этом наиболее целесообразным на современном уровне считается применение фиксированных комбинаций таких лекарств. И пациенты, и врачи должны хорошо понять необходимость длительной терапии с периодическим контролем ключевых показателей и обязательным достижением так называемых целевых уровней АД, то есть стабильной нормализации АД. Только такой подход к лечению больных АГ может дать успешный результат. Но в настоящее время, как было указано выше, только очень небольшое количество больных АГ лечится эффективно. В этой связи в Украине не наблюдается снижение частоты осложнений данного заболевания.

Specialists of the Laboratory of Epidemiological Research and Medical Informatics of the State Institution “Institute of Public Health named after A.I. O.M. Marzeeva NAMNU” researched the issues of health status, its subjective feeling, as well as behavior that contributes to health or is risky among people of all ages. Assessment by adolescents and young people of their own health, life satisfaction is important for the development of both preventive programs and directions for promoting health. At the same time, it is also important for the elderly and elderly to maintain an active lifestyle, maintain health, work (self-realization), and overcome the so-called biological determinism. It is reasonable to consider the social environment as an important determinant of health. In this regard, the question of optimizing the social environment arises, since in the absence of a comfortable social environment focused on human development, there are actually no constructive conditions for the formation of good health.

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If a patient tests positive for SARS-CoV-2 and/or develops COVID-19, discontinuation of biologics should be considered until the patient clears the infection. JAK inhibitors (tofacitinib and others) selectively affect the intracellular JAK/STAT signaling system, which mediates the action of many cytokines involved in the pathogenesis of ulcerative colitis. Unlike genetically engineered biological drugs, inhibition


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