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The last (seventh) category includes artificial (trophic) changes in facial tissues that occurred in patients with artificial lung ventilation and due to prolonged lying on the stomach. The classifications given were the first descriptions of skin lesions in COVID-19 and therefore different signs were given: those that were caused specifically by COVID-19, and those that arose due to various causes, in particular those associated with the treatment of the disease. Due to the fact that these lesions required different approaches in both treatment and anti-epidemic or precautionary measures, we, based on the experience of all these months of observation of patients, propose a classification of skin lesions associated with COVID-19. lay out like this

Лечение кортикостероидами (особенно преднизолоном в дозе ≥20 мг/сут или его эквивалент) связано с повышенным риском инфицирования. Однако неясно, связана ли терапия кортикостероидами с повышенным риском развития COVID-19 или ее осложнений. Данные о будесониде , кортикостероидах местного действия с низкой системной биодоступностью показывают, что эти препараты связаны со значительно меньшим количеством побочных эффектов по сравнению с системными кортикостероидами и их побочные эффекты приближены к плацебо.

If a patient tests positive for SARS-CoV-2 and/or develops COVID-19, discontinuation of biologics should be considered until the patient clears the infection. JAK inhibitors (tofacitinib and others) selectively affect the intracellular JAK/STAT signaling system, which mediates the action of many cytokines involved in the pathogenesis of ulcerative colitis. Unlike genetically engineered biological drugs, inhibition

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According to him, now there are 5.5 thousand patients in hospitals who have been diagnosed with coronavirus disease. Of these, 2,300 are on beds with oxygen therapy, and most of them receive it. To prevent logistical problems, at the end of last year, state funding was allocated through several mechanisms: one in the form of centralized purchases, one in the form of subventions provided to the regions in order to purchase autonomous sources of oxygen supply. On September 15, the Ministry of Health sent 124,608 packages of the Paxclovid drug for coronavirus disease to the regions. The medicine is prescribed primarily to patients at risk to prevent the complex course of coronavirus disease.


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