If a patient tests positive for SARS-CoV-2 and/or develops COVID-19, discontinuation of biologics should be considered until the patient clears the infection. JAK inhibitors (tofacitinib and others) selectively affect the intracellular JAK/STAT signaling system, which mediates the action of many cytokines involved in the pathogenesis of ulcerative colitis. Unlike genetically engineered biological drugs, inhibition
"Второй месяц мы видим рост количества заболеваний коронавирусной болезнью. За прошедшую неделю зафиксировали 24 тысячи новых случаев, неделю до этого было 16 тысяч, то есть происходит постепенный рост. Наши эксперты вместе с экспертами ВОЗ прогнозируют, что в этом году пик заболеваемости будет в начале октября . В предыдущие годы это был конец октября — начало ноября. К этому мы готовимся, чтобы оказывать должную медицинскую помощь", — рассказал министр.
The first and mandatory step in the treatment of hypertension is lifestyle modification (LS), which is aimed at correcting the above risk factors, primarily modifiable ones. A big problem is the choice of the most optimal treatment for hypertension, which can slow down the progression of lesions of the heart, blood vessels, kidneys, brain and eyes. The vast majority of hypertensive patients who seek medical help require combination antihypertensive therapy. At the same time, the most appropriate at the present level is the use of fixed combinations of such drugs.
The criteria for assessing their own health by young people (25-44 years old - according to the WHO classification) were distributed as follows: almost half of the respondents, regardless of gender, rated their own health as "good"; every 4th of those surveyed - as "very good"; “Mediocre” health was noted by every fifth woman and every tenth person; almost the same was the proportion of respondents who rated their own health as “bad”; the level of subjective assessment of "excellent health" was observed in every tenth man, while in women it was absent.